Inflammatory patterns in patients with chronic hepatitis C
نویسندگان
چکیده
Methods We performed a cross-sectional study on patients with CHC, in a tertiary-care hospital in November 2011 – April 2012. We staged liver fibrosis using FibroMax (BioPredictive) and we used CobasTaqman (Roche) for HCV-RNA quantification. Patients were also evaluated by ALT, platelets, erythrocyte sedimentation rate (ESR), fibrinogen, C-reactive protein (CRP) and tumor necrosis factor alpha (TNFa) plasma levels. For TNFa quantification we used Kamiya Biomedical Company ELISA kits.
منابع مشابه
Expression of Human Cytokine Genes Associated with Chronic Hepatitis B Disease Progression
Background: Hepatitis viruses are non-cytopathic viruses that lead to the infection and pathogenesis of liver diseases as a result of immunologically mediated event. Objective: To investigate the expression of human inflammatory cytokines in chronic hepatitis B patients according to the severity of the infection. Methods: We recruited a total of 120 patients, 40 of whom from cirrhotic, 40 non-c...
متن کاملSero-Epidemiology of Hepatitis E Infections in patients with chronic Hepatitis C virus infection in Jahrom, Southern Iran
Background and Aims: Co-infection of hepatitis E virus (HEV) in chronic hepatitis C virus (HCV) infected patients can develop and increase liver disease and hepatic complications in the world. The purpose of this study was to assess the prevalence of HEV infection in patients suffering from chronic HCV infection. Materials and Methods: Cross-sectional study testing anti-HEV antibodies in serum...
متن کاملCHARACTERISTICS AND PREVALENCE OF OCCULT HEPATITIS B VIRUS INFECTION IN PATIENTS WITH HEPATITIS C IN IRAN
ABSTRACT Background: Hepatitis B virus (HBV) infection in patients who lack detectable hepatitis B surface antigen (HBsAg) is called occult hepatitis B infection. Such infections have been frequently identified in patients with chronic hepatitis Cliver disease, but their prevalence is not known. Methods: 207 patients with chronic hepatitis C who were HCV -RNA and antiHCV positive were stu...
متن کاملبررسی میزان شیوع پادتن ضد ویروس هپاتیت HCV-Ab) C) در بیماران پسوریازیسی شهر کرمان
Psoriasis is a chronic inflammatory skin disease that in most cases has no specific etiology. It has been reported in some articles that some relationship may exist between psoriasis and hepatitis C virus. For this reason, this study was done to determine the prevalence of hepatitis C antibody in psoriatic patients in Kerman. In this study, 132 patients with psoriasis...
متن کاملارزیابی و مقایسه کیفیت زندگی بیماران مبتلا به هپاتیت B و C مزمن با افراد سالم در استان همدان
Introduction & Objective: Chronic hepatitis B and C will result in limitation of physical and mental functions which in turn reduce the quality of life (QOL) of the patients. The aim of this study was to determine the quality of life among chronic hepatitis B and/or C patients in Hamadan province from March 2011 to March 2012. Materials & Methods: A case- control study was done using SF-36 qu...
متن کاملMolecular Detection of HGV RNA in Chronic Hepatitis Patients from Afzalipoor General Hospital in Kerman, Iran
Background and Aims: Viral hepatitis is a global health problem with a high mortality rate. Recently, a new Flavi-like virus, provisionally named hepatitis G virus (HGV), has been described. HGV does not induce an immune response that is consistently detectable by using recombinant proteins from prokaryotic expression, therefore studies have been conducted by using polymerase chain reaction (...
متن کامل